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Dr Trung Ngo
Trung completed his PhD in Neuroscience with eminent Australian neurobiologist, Jack Pettigrew, at the University of Queensland. His research studies employed caloric vestibular stimulation (CVS) — a simple, non-invasive (unihemispheric) brain stimulation technique— to demonstrate evidence for a novel neural mechanism of visual rivalry: the interhemispheric switch (IHS) model.
Trung was awarded an NHMRC postdoctoral clinical research fellowship to continue investigating rivalry mechanisms and characterise rivalry abnormalities in psychiatric groups. In particular, the project examined
His research is currently based at QIMR Berghofer’s Genetic Epidemiology Laboratory, involving the collaborative development of a new online BR test (with
Research/Industry Collaboration Interests & PhD/DPsych projects
[A] Systems- to genetic-level mechanisms, individual differences (
[B] Development of integrated/portable hardware (devices) and software applications for (i) perceptual rivalry viewing (e.g., 3D displays), data collection and analyses; (ii) probing IHS rhythms (
[C] Multi-platform development of candidate endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
[D] Clinical applications of non-invasive vestibular neuromodulation, and the genetics and neuroimaging of its therapeutic response, with the aim of characterising novel electroceutical pathways and response biomarkers (e.g., gene-based associations with neuroplastic networks/pathways) across a spectrum of psychiatric and neurological diseases.
[E] Investigating the thesis that bistable (anti-phase) interhemispheric oscillations are a fundamental neurobiological mechanism — given they’re widely observed in several species (e.g., rodents, birds, cetaceans, humans, Drosophila) across diverse phenotypes such as biological rhythms (e.g., sleep/wake and menstrual cycles), autonomic functions, oculomotor activity, perception/attention and mood/behaviour changes. Investigations in this area will aim to determine whether the underlying genes, molecular mechanisms and neural network dynamics are conserved in nature, with significant implications for elucidating their potential clinical utility (e.g., early psychosis, BD, depression, PTSD).
Law PCF, Riddiford JA, Paton BK, Gurvich CT, Ngo TT, Miller SM (2015). No relationship between binocular rivalry rate and eye-movement profiles in healthy individuals: A Bayes factor analysis. Perception 44 (6): 643–661.
Ngo TT, Liu GB, Tilley AJ, Pettigrew JD, Miller SM (2007). Caloric vestibular stimulation reveals discrete neural mechanisms for coherence rivalry and eye rivalry: A meta-rivalry model. Vision Research 47 (21): 2685–2699.
Law PCF, Paton BK, Thomson RH, Liu GB, Miller SM, Ngo TT (2013). Dichoptic viewing methods for binocular rivalry research: Prospects for large-scale clinical and genetic studies. Twin Research and Human Genetics 16 (6): 1033–1078.
Miller SM, Ngo TT (2007). Studies of caloric vestibular stimulation: Implications for the cognitive neurosciences, the clinical neurosciences and neurophilosophy. Acta Neuropsychiatrica 19 (3): 183–203.
Ngo TT, Barsdell WN, Law PCF, Miller SM (2013). Binocular rivalry, brain stimulation and bipolar disorder. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 211–252). Advances in Consciousness Research (Vol. 90). Amsterdam, The Netherlands: John Benjamins Publishing Company.
Wade NJ, Ngo TT (2013). Early views on binocular rivalry. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 77–108). Advances in Consciousness Research (Vol. 90). Amsterdam, The Netherlands: John Benjamins Publishing Company.