New studies for Women with Depression

MAPrc has introduced two new clinical trials for both young and older women who are experiencing depression.
CLICK HERE to read more about new treatments for perimenopausal women

Common symptoms of depression include:

  • Feelings of helplessness and hopelessness
  • Appetite or weight changes
  • Sleep changes
  • Anger and irritability
  • Loss of energy
  • Lack of interest in everyday activities

Common symptoms of menopause include:

  • Hot flushes
  • Migraines
  • Rapid heart rate
  • Urinary frequency or incontinence
  • Memory loss
  • Fatigue


Dr Charlotte Keating is running a clinical trial of oxytocin nasal spray and an estrogen tablet for young women experiencing treatment resistant depression.

The aim of the study is to demonstrate the efficacy of adding oxytocin and estrogen (tibolone) to selective serotonin reuptake inhibitors (SSRIs), to improve response to SSRIs in women with a history of treatment resistance depression.
To take part in this study you must be female, physically well, have a diagnosis of depression, be between the ages of 18-45 and able to give informed consent.

For further details click here or contact Dr Charlotte Keating on 9076 5180 or email 


All women experience menopause and a significant number suffer from ongoing, severe depression beginning with the major hormone fluctuations in this middle stage of life.  We know that the brain and mental state is affected by fluctuating hormone systems about five years before the common physical symptoms of hot flushes and cessation of the menstrual period.

In order to discover the best treatment approach for this understudied depression that affects a large proportion of women in their forties and fifties, we are currently undertaking several clinical research studies.

We are looking for women who are aged 40 - 65, experiencing symptoms of menopause, experiencing depression and is interested in participating in research.

For further details contact Emmy Gavrilidis on 9076 6913 or email

CLICK HERE to complete a rating scale to detect depression in menopause



 MAPrc Monash Alfred Psychiatry Research Centre, Level 4, 607 St Kilda Road, Melbourne 3004

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