Women's Mental Health

Mental illness has many gender-specific aspects that clinical research has not always addressed. For example, in conditions such as schizophrenia, the age of onset and pattern of symptoms commonly seen is different for women and men. Women and men may also respond differently to medications or other treatments. In addition, changes in the level of sex hormones such as estrogen are known to affect symptoms.

The Women’s Mental Health team is working on numerous aspects of women’s mental health, the experiences of women with mental illness and potential options for treatment. 

One particular focus of our research is the role of the neuroendocrine system in mental illnesses, and specifically the use of female hormones to improve the results of treatment. We are conducting ground-breaking research into the use of estrogen to improve symptoms in schizophrenia and the use of selective brain estrogens in postmenopausal women. We are also exploring possible links between the oral contraceptive pill and depression.

Another important project is NRAMP, the National Register of Antipsychotic Medications in Pregnancy. This is the first register of its kind worldwide. NRAMP aims to create a database of information about the effects of antipsychotic medications taken during pregnancy and the postnatal period. More information about NRAMP is available here. 

To find out more about current projects click here. For information about our PTSD clinical trial, please click here

Women’s Mental Health Research Division

Director
Professor Jayashri Kulkarni